Product activity:
Protein tyrosine kinases (PTKs) are key molecules in signaling pathways and important targets in drug development. Two classes of tyrosine kinases exist in cells: receptor tyrosine kinases and non-receptor tyrosine kinases. Receptor tyrosine kinases include insulin receptors and various growth factor receptors, such as EGFR, FGFR, VEGFR, NGFR, etc. Receptor tyrosine kinases are a class of transmembrane proteins that can be activated by corresponding ligands to transmit extracellular signals to the cytoplasm by phosphorylating tyrosine residues on autoreceptors (autophosphorylation) and downstream signaling proteins middle. The main roles of PTKs include regulating the multicellular functions of the body. Intercellular signals for growth, differentiation, adhesion, motility and death are often transmitted through tyrosine kinases. In humans, tyrosine kinases play important roles in the development of many diseases, including diabetes and cancer.
MCE contains more than 700 products related to tyrosine kinase signaling pathway, which can be used for tyrosine kinase related drug screening and disease research.
  Product advantages:
700+ tyrosine kinase related compounds, which can be used for high-throughput screening and high-content screening.
It is a useful tool for the study of tyrosine kinase-related diseases.
Diverse structures, high medicinal activity and cell permeability.
Provide detailed biological activity and chemical information of each product, and include LC/MS, NMR and other quality inspection reports, which are convenient for customers to use.
  product manual:
Packaging: 96 cryovials / 96-well plate / 384-well plate;
Specifications: 30uL; 50uL; 100uL; 200uL or other customized volume, pre-dissolved in DMSO, water or ethanol;
Shelf life: -80℃ for two years; -20℃ for one year;